Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR-375/KLF4 pathway to attenuate atherosclerosis

Author:

Chen WennaORCID,Li Ximing,Guo Shengnan,Song Nan,Wang Junyan,Jia Lianqun,Zhu Aisong

Funder

National Natural Science Foundation of China

Key Basic Research Project of Liaoning Ministry of Education

Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications

Liaoning University of Traditional Chinese Medicine

Young and Middle-aged Science and Technology Innovation Talent Support Plan of Shenyang

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference45 articles.

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3. Bouhlel MA, Derudas B, Rigamonti E, Dièvart R, Brozek J, et al. PPARg activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab.. 6 (2007)137–143.

4. Alternative activation of macrophages: mechanism and functions;Gordon;Immunity,2010

5. Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, et al. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ. Res.. 107 (2010) 737–746.

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