Ginsenoside compound K exerts anti-inflammatory effects through transcriptional activation and transcriptional inhibition of glucocorticoid receptor in rheumatoid arthritis fibroblast-like synoviocytes
Author:
Funder
National Natural Science Foundation of China
University Natural Science Research Project of Anhui Province
Publisher
Elsevier BV
Subject
Pharmacology,Immunology,Immunology and Allergy
Reference29 articles.
1. Ginsenoside Compound K Protects against Obesity through Pharmacological Targeting of Glucocorticoid Receptor to Activate Lipophagy and Lipid Metabolism;Yang;Pharmaceutics.,2022
2. Ginsenoside compound K- a potential drug for rheumatoid arthritis;Tang;Pharmacol. Res.,2021
3. Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis;Zhang;Inflammopharmacology,2019
4. Ginsenoside metabolite compound K suppresses T-cell priming via modulation of dendritic cell trafficking and costimulatory signals, resulting in alleviation of collagen-induced arthritis;Chen;J. Pharmacol. Exp. Ther.,2015
5. Combination therapy of ginsenoside compound K and methotrexate was efficient in elimination of anaemia and reduction of disease activity in adjuvant-induced arthritis rats;Chen;Pharm. Biol.,2020
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2. Ginsenoside compound K plays an anti-inflammatory effect without inducing glucose metabolism disorder in adjuvant-induced arthritis rats;Food & Function;2024
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