KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage

Author:

Ergashev Akmal,Shi Fengyu,Liu Zhu,Pan Zhenyan,Xie Haonan,Kong Lingming,Wu Lijun,Sun Hongwei,Jin Yuepeng,Kong Hongru,Geng Dandan,Ibrohimov Alisherjon,Obeng Enoch,Wang Yi,Ma Feng,Chen GangORCID,Zhang Tan

Funder

National Natural Science Foundation of China

Science and Technology Planning Social Development Project of Zhenjiang City

Science and Technology Plan Project of Wenzhou Municipality

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference63 articles.

1. Whole-exome sequencing identifies SLC52A1 and ZNF106 variants as novel genetic risk factors for (early) multiple-organ failure in acute pancreatitis;van den Berg;Ann. Surg.,2022

2. Deletion of macrophage migration inhibitory factor ameliorates inflammation in mice model severe acute pancreatitis;Zhu;Biomed. Pharmacother.,2020

3. Butyrate ameliorates caerulein‐induced acute pancreatitis and associated intestinal injury by tissue‐specific mechanisms;Pan;Br. J. Pharmacol.,2019

4. Aspirin protects against acinar cells necrosis in severe acute pancreatitis in mice;Lu;BioMed Res. Int.,2016

5. Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway, Oxidative Medicine and Cellular Longevity 2018;Liu,2018

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