Inhibition of the C3a receptor attenuates sepsis-induced acute lung injury by suppressing pyroptosis of the pulmonary vascular endothelial cells

Author:

Feng Quan-rui,Zhang Yong-Sheng,Zhuang Yang-fan,Xie Zhen-xing,Bai Xiang-jun,Li Zhan-fei,Wang Yu-chang

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference30 articles.

1. Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome;Englert;JCI Insight,2019

2. Inflammatory caspases drive pyroptosis in acute lung injury;Liu;Front. Pharmacol.,2021

3. The pyrin inflammasome in Health and disease;Schnappauf;Front. Immunol.,2019

4. Caspase-1-dependent pyroptosis of peripheral blood mononuclear cells predicts the development of sepsis in severe trauma patients: a prospective observational study;Wang;Medicine (Baltim.),2018

5. Caspase-1-Dependent pyroptosis of peripheral blood mononuclear cells is associated with the severity and mortality of septic patients;Wang;Biomed Res Int 2020,2020

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