Tetrahydroxystilbene glucoside extends mouse life span via upregulating neural klotho and downregulating neural insulin or insulin-like growth factor 1

Author:

Zhou Xuanxuan,Yang Qian,Xie Yanhua,Sun Jiyuan,Hu Jing,Qiu Pengcheng,Cao Wei,Wang Siwang

Funder

New Drug Create Engineering Technology Research Center

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Clinical Neurology,Ageing,General Neuroscience

Reference84 articles.

1. The endothelium abridges insulin resistance to premature aging;Avogaro;J. Am. Heart Assoc.,2013

2. Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging;Bartke;Endocrinology,2005

3. Long-lived klotho mice: new insights into the roles of IGF-1 and insulin in aging;Bartke;Trends Endocrinol. Metab.,2006

4. Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights;Bartke;Biogerontology,2003

5. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function;Barton-Davis;Proc. Natl. Acad. Sci. U. S. A,1998

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