ApoE genotype accounts for the vast majority of AD risk and AD pathology

Author:

Raber Jacob,Huang Yadong,Ashford J.Wesson

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Clinical Neurology,Ageing,General Neuroscience

Reference64 articles.

1. Alzheimer’s disease as a disorder of mechanisms underlying structural brain self-organization;Arendt;Neuroscience,2001

2. Ashford JW, Mattson M, Kumar V. Neurobiological systems disrupted. In: Kumar V, Eisdorfer C, editors. Advances in the diagnosis and treatment of Alzheimer’s disease. New York: Springer Publishing Company; 1998.

3. Non-familial Alzheimer’s disease is mainly due to genetic factors;Ashford;J. Alzheimer’s Dis.,2002

4. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition;Bales;Nat. Genet.,1997

5. Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer’s disease;Bales;Proc. Natl. Acad. Sci. USA,1999

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