Proteasome inhibition: a novel approach to cancer therapy

Author:

Adams Julian

Publisher

Elsevier BV

Subject

Molecular Biology,Molecular Medicine

Reference34 articles.

1. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules;Rock;Cell,1994

2. Proteasome inhibitors: a novel class of potent and effective antitumor agents;Adams;Cancer Res.,1999

3. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition;An;Leukemia,2000

4. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells;Hideshima;Cancer Res.,2001

5. Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation;Masdehors;Leuk. Lymphoma,2000

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