Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction

Author:

Han Min Ho,Kim Gi-Young,Yoo Young Hyun,Choi Yung Hyun

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference56 articles.

1. The Bcl-2 apoptotic switch in cancer development and therapy;Adams;Oncogene,2007

2. Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery;Adhami;Molecular Cancer Therapeutics,2004

3. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells;Ahmad;Clinical Cancer Research,2000

4. Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins;Ahsan;Cancer Letters,2007

5. Analysis of functional elements in the human Egr-1 gene promoter;Aicher;Rheumatology International,1999

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