Anti-ricin toxin human neutralizing antibodies and DMAbs protection against ricin toxin poisoning

Author:

Yu Haotian,Wu Meng,Zhao Na,Dong Mingxin,Wang Yan,Yu Kaikai,Sun Chengbiao,Xu Na,Ge Liangpeng,Liu Wensen

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference30 articles.

1. Ricin poisoning: a comprehensive review;Audi;JAMA,2005

2. Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase;Bellisola;Biochem. Pharmacol.,2004

3. Identification and characterization of a monoclonal antibody recognizing a galactose-binding domain of the toxin ricin;Colombatti;J. Immunol.,1987

4. Expi293 Expression System [Internet]. [cited 2017 Jun 13]. Available from: http://www.thermofisher.com/ug/en/home/life-science/protein-biology/protein-expression/mammalian-protein-expression/transient-mammalian-protein-expression/expi293-expression-system.html.html?gclid=Cj0KEQjwmv7JBRDXkMWW4_Tf8ZoBEiQA11B2fqYbB31lW1La5FohMYdPeobx4H0WVv_xmrRNs4SlHMIaAgSb8P8HAQ&ef_id=WFBkEQAABM@NpM6E:20170613124108:s.

5. Ricin toxin contains at least three galactose-binding sites located in B chain subdomains 1 alpha, 1 beta, and 2 gamma;Frankel;Biochemistry,1996

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