Utilizing metabolism-based structure-activity relationships and biokinetic modeling for toxicological evaluation: A case study on L-menthyl D-Lactate

Author:

Ellison CorieORCID,Blubaugh Jillian,Engled Sierra,Karb Mike,Lester Cathy,Obringer Cindy,Woeller Kara

Publisher

Elsevier BV

Reference66 articles.

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2. Update to RIFM fragrance ingredient safety assessment, l-menthyl D-lactate, CAS registry number 59259-38-0;Api;Food Chem. Toxicol.,2024

3. Developing an internal threshold of toxicological concern (iTTC);Arnot;J. Expo. Sci. Environ. Epidemiol.,2022

4. The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study;Ball;Regul. Toxicol. Pharmacol.,2014

5. Applicability of physicochemical data, QSARs and read-across in threshold of toxicological concern assessment;Bassan;EFSA Support. Publ.,2011

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