Review of the impact of fragment-based drug design on PROTAC degrader discovery-Reference-Cited by-同舟云学术

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Review of the impact of fragment-based drug design on PROTAC degrader discovery

Published:2024-02 Issue: Volume:171 Page:117539
ISSN:0165-9936
Container-title:TrAC Trends in Analytical Chemistry
language:en
Short-container-title:TrAC Trends in Analytical Chemistry

Author:

Chen Peiqi,Li Qiang,Lei Xiaoguang^ORCID

Publisher

Elsevier BV

Reference84 articles.

1. PROTAC targeted protein degraders: the past is prologue;Békés;Nat. Rev. Drug Discov.,2022

2. Proteolysis-targeting chimeras: harnessing the ubiquiting-proteasome system to induce degradation of specific target proteins;Goleman;Annu. Rev. Cancer. Biol.,2018

3. What is the right dose? The elusive optimal biologic dose in phase I clinical trials;Adjei;J. Clin. Oncol.,2006

4. Catalytic in vivo protein knockdown by small-molecule PROTACS;Bondeson;Nat. Chem. Biol.,2015

5. PROTAC technology: opportunities and challenges;Gao;ACS Med. Chem. Lett.,2020

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