Quantitative detection of residual porcine host cell DNA by real-time PCR

Author:

Chang Jen-Ting,Chen Yu-Chen,Chou Yu-Chi,Wang Shih-Rong

Publisher

Elsevier BV

Subject

Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Reference34 articles.

1. Detection and elimination of cellular nucleic acids in biologicals produced on continuous cell lines;van Wezel;Dev Biol Stand,1981

2. Quantitation of DNA and protein impurities in biopharmaceuticals;Briggs;Anal Chem,1991

3. Risk assessment on the carcinogenic potential of hybridoma cell DNA: implications for residual contaminating cellular DNA in biological products;Dortant;Biologicals,1997

4. A probabilistic model for risk assessment of residual host cell DNA in biological products;Yang;Vaccine,2010

5. Viral vaccines and residual cellular DNA;Horaud;Biologicals,1995

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