Site-directed mutagenesis of tissue factor pathway inhibitor–binding exosite D60A on factor VII results in a new factor VII variant with lower coagulant activity

Author:

Seanoon Karnsasin,Kitiyanant Vorawat,Payongsri Panwajee,Sirachainan Nongnuch,Angchaisuksiri Pantep,Chuansumrit Ampaiwan,Hongeng Suradej,Tanratana Pansakorn

Funder

ISTH

Publisher

Elsevier BV

Subject

Hematology

Reference64 articles.

1. Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII;Bolt;Glycobiology,2005

2. Factor VII deficiency;Perry;Br J Haematol,2002

3. In vitro expression of mutant factor VII proteins and characterization of their clinical significance;Mashayekhi;Mol Med Rep,2018

4. Expression of recombinant human coagulation factor VII by the Lizard Leishmania expression system;Mirzaahmadi;J Biomed Biotechnol,2011

5. Novel sites of gamma carboxylation in human factor VII;Wilkerson;Blood,2016

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