In vitro-derived insulin-producing cells modulate Th1 immune responses and induce IL-10 in streptozotocin-induced mouse model of pancreatic insulitis

Author:

Daryabor Gholamreza,Shiri Esmaeil Hashemi,Amirghofran Zahra,Kamali-Sarvestani Eskandar

Funder

Shiraz University of Medical Sciences

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference40 articles.

1. Fifty years of pancreatic islet pathology in human type 1 diabetes: insights gained and progress made;Morgan;Diabetologia,2018

2. Pancreatic beta cell death: novel potential mechanisms in diabetes therapy;Rojas;J Diabetes Res,2018

3. Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes;Bradley;J Immunol,1999

4. GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice;Zekzer;J Clin Invest,1998

5. Type I interferon is a catastrophic feature of the diabetic islet microenvironment;Newby;Front Endocrinol,2017

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