Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial

Author:

Cortes Javier,Cescon David W,Rugo Hope S,Nowecki Zbigniew,Im Seock-Ah,Yusof Mastura Md,Gallardo Carlos,Lipatov Oleg,Barrios Carlos H,Holgado Esther,Iwata Hiroji,Masuda Norikazu,Otero Marco Torregroza,Gokmen Erhan,Loi Sherene,Guo Zifang,Zhao Jing,Aktan Gursel,Karantza Vassiliki,Schmid Peter,Luis Fein,Gonzalo Gomez Abuin,Diego Kaen,Ruben Kowalwszyn,Matias Molina,Mirta Varela,Sally Baron-Hay,Stephen Begbie,Philip Clingan,Sherene Loi,Dhanusha Sabanathan,Andrea Gombos,Donatienne Taylor,Carlos Barrios,Leandro Brust,Fabiano Costa,Ruffo de Freitas Junior,Roberto Hegg,Domicio Carvalho Lacerda,Fernando Cezar Toniazzi Lissa,Roberto Odebrecht Rocha,Antonio Orlando Scalabrini Neto,Felipe Silva,David Cescon,Danielle Charpentier,Cristiano Ferrario,Xinni Song,Joanne Yu,Alejandro Acevedo,Carlos Gallardo,Claudio Salas,Cesar Sanchez,Eduardo Yanez,Alvaro Gomez Diaz,Jesus Sanchez,Petra Holeckova,Zdenek Kral,Bohuslav Melichar,Katarina Petrakova,Jana Prausova,Vesna Glavicic,Erik Jakobsen,Jeanette Jensen,Soren Linnet,Tamas Lorincz,Herve Bonnefoi,Isabelle Desmoulins,Anthony Goncalves,Anne-Claire Hardy-Bessard,Luis Teixeira,Jens-Uwe Blohmer,Peter Fasching,Dirk Forstmeyer,Nadia Harbeck,Jens Huober,Anna Kaczerowsky Flores de Sousa,Christian Kurbacher,Sibylle Loibl,Diana Lueftner,Tjoung-Won Park-Simon,Raquel Von Schumann,Pauline Wimberger,Louis Chow,Ava Kwong,Kai Cheong Roger Ngan,Peter Arkosy,Tibor Csoszi,Zsuzsanna Kahan,Laszlo Landherr,Karoly Mahr,Gabor Rubovszky,John Crown,Catherine Kelly,Seamus O'Reilly,Saverio Cinieri,Antonietta DAlessio,Enrico Ricevuto,Tomoyuki Aruga,Takaaki Fujii,Kenichi Inoue,Takashi Ishikawa,Yoshinori Ito,Tsutomu Iwasa,Hiroji Iwata,Yoshimasa Kosaka,Koji Matsumoto,Yasuo Miyoshi,Hirofumi Mukai,Seigo Nakamura,Naoki Niikura,Shoichiro Ohtani,Akihiko Osaki,Yasuaki Sagara,Eiji Suzuki,Masato Takahashi,Yuko Tanabe,Kenji Tamura,Koichiro Tsugawa,Junichiro Watanabe,Naohito Yamamoto,Yutaka Yamamoto,Teruo Yamauchi,Anita Bustam,Mastura Md Yusof,Angel Gomez Villanueva,Alejandro Juarez Ramiro,Jorge Martinez Rodriguez,Flavia Morales-Vasquez,Jessica Reyes Contreras,Karin Beelen,Vivianne Tjan-Heijnen,David Porter,Ewa Chmielowska,Ewa Nowakowska-Zajdel,Zbigniew Nowecki,Barbara Radecka,Joanna Streb,Cezary Szczylik,Rafal Tarnawski,Bogdan Zurawski,Alexander Arkhipov,Natalia Fadeeva,Oleg Lipatov,Andrey Meshcheryakov,Vladimir Moiseyenko,Guzel Mukhametshina,Jin Hee Ahn,Seock-Ah Im,Keun Seok Lee,Kwong Hwa Park,Yeon Hee Park,Begona Bermejo de las Heras,Javier Cortes,Josefina Cruz Jurado,Luis de la Cruz Merino,Jose Garcia Saenz,Maria Gion,Esther Holgado,Esther Zamora Adelantado,Chien-Ting Liu,Mei-Ching Liu,Chiun-Sheng Huang,Chao-Jung Tsao,Ling-Ming Tseng,Cagatay Arslan,Gul Basaran,Irfan Cicin,Erhan Gokmen,Seyda Gunduz,Nil Molinas Mandel,Mustafa Ozguroglu,Ozgur Ozyilkan,Sinan Yavuz,Steve Chan,Janine Graham,Iain MacPherson,Peter Schmid,Nicholas Turner,Mark Tuthill,Christopher Twelves,Duncan Wheatley,Hryhoriy Adamchuk,Oleksandr Berzoy,Igor Bondarenko,Oleksii Kolesnik,Olena Kolesnik,Hanna Komisarenko,Anna Kryzhanivska,Iurii Leshchenko,Alla Nasonova,Natalya Otchenash,Olga Ponomarova,Andrii Rusyn,Sergii Shevnya,Yaroslav Shparyk,Dmytro Trukhin,Grygorii Ursol,Ihor Vynnychenko,Sibel Blau,Madhu Chaudhry,Michael Chung,Patrick Cobb,Scott Cole,Jennifer Diamond,Keerthi Gogineni,Jeffrey Hargis,Kent Hoskins,William Irvin,Randa Loutfi,Janice Lu,Raul Mena,Susan Moore,Rita Nanda,Ira Oliff,Coral Omene,Timothy Panella,Amit Panwalkar,Brian Patson,Hope Rugo,Irina Rybalova,Michael Schleider,Robert Siegel,Michael Simon,Laura Stampleman,Bradley Sumrall,Michaela Tsai,Frances Valdes-Albini

Publisher

Elsevier BV

Subject

General Medicine

Reference27 articles.

1. Pattern of metastatic spread in triple-negative breast cancer;Dent;Breast Cancer Res Treat,2009

2. Survival outcomes for patients with metastatic triple-negative breast cancer: implications for clinical practice and trial design;Kassam;Clin Breast Cancer,2009

3. Triple-negative breast cancer: adjuvant therapeutic options;Gucalp;Chemother Res Pract,2011

4. Triple-negative breast cancer: are we making headway at least?;Arnedos;Ther Adv Med Oncol,2012

5. Immune regulation of cancer;Disis;J Clin Oncol,2010

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