Danshen injection induces autophagy in podocytes to alleviate nephrotic syndrome via the PI3K/AKT/mTOR pathway

Author:

Chen Junqi,Yuan Shengliang,Zhou Jie,Huang Xiuye,Wu Wenjia,Cao Yiwen,Liu HongORCID,Hu Qinghong,Li Xiaojie,Guan Xueping,Yin Simin,Jiang Jiaying,Zhou Yuan,Zhou Jiuyao

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference32 articles.

1. Cryptotanshinone ameliorates renal ischaemia-reperfusion injury by inhibiting apoptosis and inflammatory response;Bai;Basic Clin. Pharmacol. Toxicol.,2019

2. Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy;Barutta;Autophagy,2022

3. The clinical efficacy of compound Danshen injection on acute cerebral infarction and on the changes in the CRP, d-dimer, and IL-6 levels;Bian;Am. J. Transl. Res.,2021

4. Management of congenital nephrotic syndrome: consensus recommendations of the ERKNet-ESPN Working Group;Boyer;Nat. Rev. Nephrol.,2021

5. JAK/STAT pathway promotes the progression of diabetic kidney disease via autophagy in podocytes;Chen;Eur. J. Pharmacol.,2021

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