The bioavailability enhancement and insight into the action mechanism of poorly soluble natural compounds from co-crystals preparation: Oridonin as an example

Author:

Jia Xin-ming,Hao Han,Zhang Qian,Yang Meng-xin,Wang Nan,Sun Shi-lin,Yang Ze-nan,Jin Yi-ran,Wang Jing,Du Ying-fengORCID

Funder

Natural Science Foundation of Hebei Province

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference56 articles.

1. Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis;Bohanon;J. Surg. Res.,2014

2. Synergistic antitumor activity of oridonin and arsenic trioxide on hepatocellular carcinoma cells;Chen;Int. J. Oncol.,2012

3. Research progress of pharmaceutical Co-crystal;Fan;China Pharm,2022

4. Preparation and characterization of tecovirimat⁃benzamide cocrystals;Feng;Mil. Med. Sci.,2021

5. Research advances in dissolution mechanism and physical stability of solid dispersions;Fu;Chin. J. New Drugs,2020

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