Dendrobine rescues cognitive dysfunction in diabetic encephalopathy by inhibiting ferroptosis via activating Nrf2/GPX4 axis

Author:

Shi Yu-ShengORCID,Chen Ji-Cong,Lin Lin,Cheng Ying-Zhe,Zhao Yang,Zhang Yan,Pan Xiao-DongORCID

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference28 articles.

1. Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration;Abdalkader;Front Neurosci,2018

2. Liraglutide alleviates cognitive deficit in db/db mice: involvement in oxidative stress, iron overload, and ferroptosis;An;Neurochem. Res.,2022

3. Nrf2-ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases;Buendia;PharmacolTher,2016

4. Dendrobine alleviates cellular senescence and osteoarthritis via the ROS/NF-κB axis;Chen;Int. J. Mol. Sci.,2023

5. Morphological and pathological characteristics of brain in diabetic encephalopathy;Chen;J. Alzheimers Dis.,2018

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