Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling

Author:

Guan Ying-Yun,Liu Hai-Jun,Luan Xin,Xu Jian-Rong,Lu Qin,Liu Ya-Rong,Gao Yun-Ge,Zhao Mei,Chen Hong-Zhuan,Fang Chao

Funder

National Natural Science Foundation of China

Shanghai Municipal Education Commission

Shanghai Municipal Science and Technology Commission

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference27 articles.

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2. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach;Chan;Cancer Cell,2002

3. Inhibitory effect of Raddeanin A in human non-small cell lung cancer H460 cells;Gao;Chin. J. Appl. Environ. Biol.,2010

4. Targeting angiogenesis: progress with anti-VEGF treatment with large molecules;Grothey;Nat. Rev. Clin. Oncol.,2009

5. Antiangiogenic effects of cucurbitacin-I;Kim;Arch. Pharm. Res.,2014

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