Asperolide A induces apoptosis and cell cycle arrest of human hepatoma cells with p53-Y220C mutant through p38 mediating phosphorylation of p53 (S33)
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Multidisciplinary
Reference38 articles.
1. Hepatocellular carcinoma;Vogel;Lancet,2022
2. Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48;Sun;J. Nat. Prod.,2012
3. Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells;Zhang;Cell Death Dis.,2013
4. Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway;Lv;Cell Death Dis.,2013
5. Asperolide A prevents bone metastatic breast cancer via the PI3K/AKT/mTOR/c-Fos/NFATc1 signaling pathway;Jiang;Cancer Med.,2020
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