Fabrication of pH-dependent solid dispersion for oral colon-targeted delivery of notoginsenoside R1 and its protective effects on ulcerative colitis mice

Author:

Tie Hongyun,Wang Yaru,Shang Yunxia,Li ManlinORCID,Wei Xiaohui,Wang Zhengtao

Funder

Shanghai Municipal Education Commission

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference41 articles.

1. Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12;Wang;Hum. Exp. Toxicol.,2020

2. Notoginsenoside R1 protects WI-38 cells against lipopolysaccharide-triggered injury via adjusting the miR-181a/TLR4 axis;Qian;J. Cell. Biochem.,2019

3. Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways;Yu;Sci. Rep.,2016

4. Antiproliferative effects of different plant parts of Panax notoginseng on SW480 human colorectal cancer cells;Wang;Phytother Res.,2009

5. Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation;Zhang;J. Pharmacol. Exp. Ther.,2015

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