Dual inhibition of ERK1/2 and AKT pathways is required to suppress the growth and survival of endometriotic cells and lesions
Author:
Funder
National Institute of Child Health and Human Development
Publisher
Elsevier BV
Subject
Endocrinology,Molecular Biology,Biochemistry
Reference59 articles.
1. Apoptosis in endometriosis;Agic;Gynecol. Obstet. Invest.,2009
2. Substitutions of potentially phosphorylatable serine residues of Bax reveal how they may regulate its interaction with mitochondria;Arokium;J. Biol. Chem.,2007
3. Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis;Arosh;Proc. Natl. Acad. Sci. U. S. A.,2015
4. PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: structural and pharmacological perspectives;Asati;Eur. J. Med. Chem.,2016
5. Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkB and b-catenin pathways and activation of intrinsic apoptotic mechanisms;Banu;Mol. Endocrinol.,2009
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