Recent advances on FXR-targeting therapeutics
Author:
Funder
Austrian Science Fund
Publisher
Elsevier BV
Subject
Endocrinology,Molecular Biology,Biochemistry
Reference264 articles.
1. Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype;Abu-Hayyeh;Hepatology,2013
2. The nuclear receptor FXR, but not LXR, up-regulates bile acid transporter expression in non-alcoholic fatty liver disease;Aguilar-Olivos;Ann. Hepatol.,2015
3. Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice;Akinrotimi;Hepatology,2017
4. Obeticholic acid may increase the risk of gallstone formation in susceptible patients;Al-Dury;J. Hepatol.,2019
5. An FXR agonist reduces bile acid synthesis independently of increases in FGF19 in healthy volunteers;Al-Khaifi;Gastroenterology,2018
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4. Discovery of 4-aminophenylacetamide derivatives as intestine-specific farnesoid X receptor antagonists for the potential treatment of nonalcoholic steatohepatitis;European Journal of Medicinal Chemistry;2024-01
5. Targeting Farnesoid X Receptor in Tumor and the Tumor Microenvironment: Implication for Therapy;International Journal of Molecular Sciences;2023-12-19
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