Synthesis, biological, and photophysical studies of molecular rotor-based fluorescent inhibitors of the trypanosome alternative oxidase

Author:

Cueto-Díaz Eduardo J.,Ebiloma Godwin U.,Alfayez Ibrahim A.,Ungogo Marzuq A.ORCID,Lemgruber Leandro,González-García M. Carmen,Giron Maria D.ORCID,Salto RafaelORCID,Fueyo-González Francisco José,Shiba TomooORCID,González-Vera Juan A.,Ruedas Rama Maria José,Orte AngelORCID,de Koning Harry P.,Dardonville Christophe

Funder

Japan Society for the Promotion of Science

Gobierno de Espana Ministerio de Ciencia Innovacion y Universidades

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference51 articles.

1. The drugs of sleeping sickness: their mechanisms of action and resistance, and a brief history;De Koning;Trav. Med. Infect. Dis.,2020

2. The animal trypanosomiases and their chemotherapy: a review;Giordani;Parasitology,2016

3. Properties of L-alpha-glycerophosphate oxidase and its role in the respiration of Trypanosoma rhodesiense;Grant;Biochem. J.,1960

4. Respiration of bloodstream forms of the parasite Trypanosoma brucei brucei is dependent on a plant-like alternative oxidase;Clarkson;J. Biol. Chem.,1989

5. The trypanosome alternative oxidase: a potential drug target?;Menzies;Parasitology,2016

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