Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise

Author:

Khaiwa NouraORCID,Maarouf Noor R.,Darwish Mhd H.,Alhamad Dima W.M.ORCID,Sebastian Anusha,Hamad MohamadORCID,Omar Hany A.,Orive GorkaORCID,Al-Tel Taleb H.

Funder

Terry Fox Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference82 articles.

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5. Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top I ) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?;Li;Am. J. Canc. Res.,2017

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