Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines-Reference-Cited by-同舟云学术

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Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

Published:2018-05 Issue: Volume:152 Page:101-114
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Baud Matthias G.J.^ORCID,Bauer Matthias R.,Verduci Lorena,Dingler Felix A.,Patel Ketan J.,Horil Roy Deeptee,Joerger Andreas C.,Fersht Alan R.

Funder

European Research Council

Medical Research Council

German Research Foundation

EU FP7 infrastructure grant BIOSTRUCT-X

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference58 articles.

1. Surfing the p53 network;Vogelstein;Nature,2000

2. Live or let die: the cell's response to p53;Vousden;Nat. Rev. Canc.,2002

3. p53, guardian of the genome;Lane;Nature,1992

4. Awakening guardian angels: drugging the p53 pathway;Brown;Nat. Rev. Canc.,2009

5. Mutant p53 reactivation by small molecules makes its way to the clinic;Bykov;FEBS (Fed. Eur. Biochem. Soc.) Lett.,2014

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