Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity-Reference-Cited by-同舟云学术

Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity

Published:2014-10 Issue: Volume:86 Page:122-132
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Galal Shadia A.,Khairat Sarah H.M.,Ragab Fatma A.F.,Abdelsamie Ahmed S.,Ali Mamdouh M.,Soliman Salwa M.,Mortier Jérémie,Wolber Gerhard,El Diwani Hoda I.

Funder

National Research Centre, Cairo, Egypt

Science and Technological Development Fund (STDF), Egypt

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference38 articles.

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2. Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs☆

3. Non-classical antifolates. Part 2: Synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones

4. DNA Sequence Specificity for Topoisomerase II Poisoning by the Quinoxaline Anticancer Drugs XK469 and CQS

5. XK469, a selective topoisomerase IIbeta poison

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