Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations-Reference-Cited by-同舟云学术

Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations

Published:2020-11 Issue: Volume:206 Page:112676
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Glas Carina^ORCID,Dietschreit Johannes C.B.^ORCID,Wössner Nathalie^ORCID,Urban Lars^ORCID,Ghazy Ehab,Sippl Wolfgang^ORCID,Jung Manfred,Ochsenfeld Christian^ORCID,Bracher Franz^ORCID

Funder

Deutsche Forschungsgemeinschaft

DFG

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference66 articles.

1. Small molecules as tools to study the chemical epigenetics of lysine acetylation;Schiedel;Curr. Opin. Chem. Biol.,2018

2. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase;Imai;Nature,2000

3. Characterization of five human cDNAs with homology to the yeast SIR2 gene: sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity;Frye;Biochem. Biophys. Res. Commun.,1999

4. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins;Michishita;Mol. Biol. Cell,2005

5. Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors;Liu;Chem. Biol. Drug Des.,2018

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