Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors

Author:

Mazzucato Roberta,Roberti Marinella,Capelli Anna Maria,Rancati Fabio,Biagetti Matteo,Fiorelli Claudio,Bruno Paolo,Ronchi Paolo,Bertolini Serena,Corsi Mauro,Pala DanieleORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference48 articles.

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3. Regulation of phosphoinositide 3-kinase expression in health and disease;Kok;Trends Biochem. Sci.,2009

4. PI3K signalling: the path to discovery and understanding;Vanhaesebroeck;Nat. Rev. Mol. Cell Biol.,2012

5. p110δ, A novel phosphoinositide 3-kinase in leukocytes;Vanhaesebroeck;Proc. Natl. Acad. Sci. U. S. A.,1997

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