Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference39 articles.
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3. AXL receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6;Varnum;Nature,1995
4. AXL receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion;Wimmel;Eur. J. Cancer,2001
5. AXL is a potential target for therapeutic intervention in breast cancer progression;Zhang;Cancer Res.,2008
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1. Recent discovery and development of AXL inhibitors as antitumor agents;European Journal of Medicinal Chemistry;2024-06
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