The dual-targeting mechanism of an anti-inflammatory diarylheptanoid from Curcuma zedoaria (Christm.) Roscoe with the capacity for β2-adrenoreceptor agonism and NLRP3 inhibition
Author:
Funder
Natural Science Foundation of Jiangxi Province
National Natural Science Foundation of China
Dalian Institute of Chemical Physics, Chinese Academy of Sciences
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference49 articles.
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2. Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells;Lee;Bioorg. Chem.,2019
3. Immunomodulatory effects and mechanisms of curcuma species and their bioactive compounds: a review;Yuandani;Front. Pharmacol.,2021
4. Discovery of beta2- adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography;Zhou;J. Chromatogr. A,2018
5. Curcumin inhibits the invasion and metastasis of triple negative breast cancer via Hedgehog/Gli1 signaling pathway;Li;J. Ethnopharmacol.,2022
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