Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt

Author:

Deng Li-Juan,Hu Li-Ping,Peng Qun-LongORCID,Yang Xiao-Lin,Bai Liang-Liang,Yiu Anita,Li Yong,Tian Hai-Yan,Ye Wen-Cai,Zhang Dong-Mei

Funder

Science and Technology Program of China

National Science Foundation of China

Jinan University

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference48 articles.

1. Inhibiting TGF-beta signaling in hepatocellular carcinoma;Giannelli;Biochim. Biophys. Acta,1815

2. Molecular targeted therapy for hepatocellular carcinoma;Thomas;J. Gastroenterol.,2009

3. Natural products and derivatives as leads to cell cycle pathway targets in cancer chemotherapy;Newman;Curr. Cancer Drug Targets,2002

4. PI3K/Akt signalling pathway and cancer;Fresno Vara;Cancer Treat Rev.,2004

5. Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells;Saxena;Cancer Res.,2007

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