Learnings From the Graveyard of Phase 2 and 3 Nonalcoholic Steatohepatitis Trials
Author:
Publisher
Elsevier BV
Subject
Gastroenterology,Hepatology
Reference21 articles.
1. Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): a randomized phase 2b study;Loomba;Clin Gastroenterol Hepatol,2024
2. Pegbelfermin in patients with nonalcoholic steatohepatitis and compensated cirrhosis (FALCON 2): a randomized phase 2b study;Abdelmalek;Clin Gastroenterol Hepatol,2024
3. Cenicriviroc lacked efficacy to treat liver fibrosis in nonalcoholic steatohepatitis: AURORA phase III randomized study;Anstee;Clin Gastroenterol Hepatol,2024
4. Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLD;Brunt;J Hepatol,2022
5. Topline results from a new analysis of the REGENERATE trial of obeticholic acid for the treatment of nonalcoholic steatohepatitis;Sanyal;Hepatology,2022
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1. A turning point in hepatology? EASL reflects on the first approved drug for MASH;Journal of Hepatology;2024-08
2. Inhibition of intrahepatic monocyte recruitment by Cenicriviroc and extracellular matrix degradation by MMP1 synergistically attenuate liver inflammation and fibrogenesis in vivo;Scientific Reports;2024-07-23
3. Combination Treatment in MASLD: The Next Frontier;Clinical Gastroenterology and Hepatology;2024-05
4. MASH clinical trials and drugs pipeline: An impending tsunami;Hepatology;2024-03-19
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