14 alpha-Ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol, a potent inhibitor of sterol biosynthesis, has two sites of action in cultured mammalian cells.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference61 articles.
1. Inhibition of sterol biosynthesis in L cells and mouse liver cells by 15-oxygenated sterols.
2. 14.alpha.-Ethyl-5.alpha.-cholest-7-ene-3.beta.,15.alpha.-diol, an extraordinarily potent inhibitor of sterol biosynthesis in animal cells
3. Inhibition of sterol synthesis in L cells by 14α-ethyl-5α-cholest-7-en-15α-ol-3-one at nanomolar concentrations
4. Inhibition of sterol synthesis in animal cells by 15-oxygenated sterols with the unnatural cis-c-d ring junction—5α, 14β-Cholest-7-en-15α-ol-3-one and 5α, 14β-Cholest-7-en-15β-ol-3-one
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