Oligothymidylate analogues having stereoregular, alternating methylphosphonate/phosphodiester backbones. Synthesis and physical studies.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference31 articles.
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3. Nonionic nucleic acid analogs. Synthesis and characterization of dideoxyribonucleoside methylphosphonates
4. Proton nuclear magnetic resonance studies on dideoxyribonucleoside methylphosphonates
5. Duplex formation of a nonionic oligo(deoxythymidylate) analog [heptadeoxythymidylyl-(3'-5')-deoxythymidine heptaethyl ester (d-[Tp(Et)]7T)]with poly(deoxyadenylate). Evaluation of the electrostatic interaction
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1. Solid-Phase Synthesis, Thermal Denaturation Studies, Nuclease Resistance, and Cellular Uptake of (Oligodeoxyribonucleoside)methylborane Phosphine–DNA Chimeras;Journal of the American Chemical Society;2011-06-07
2. Hybridization of phosphate-methylated DNA and natural oligonucleotides. Implications for protein-induced DNA duplex destabilization;Recueil des Travaux Chimiques des Pays-Bas;2010-09-02
3. Nuclease resistant methylphosphonate-DNA/LNA chimeric oligonucleotides;Bioorganic & Medicinal Chemistry Letters;2009-05
4. Effect of chirality of l/d-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(α-amino acid)-thymidine dimers;Chemical Communications;2009
5. Probing Enzyme Phosphoester Interactions by Combining Mutagenesis and Chemical Modification of Phosphate Ester Oxygens;Chemical Reviews;2006-06-27
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