The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference60 articles.
1. Requirement of the Drosophila raf homologue for torso function
2. Raf functions downstream of Rasl in the Sevenless signal transduction pathway
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1. Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements;Communications Biology;2024-03-02
2. Hsp90 provides a platform for kinase dephosphorylation by PP5;Nature Communications;2023-04-17
3. Hsp70/Hsp90 organizing protein (HOP) maintains CRAF kinase activity and regulates MAPK signaling by enhancing Hsp90-CRAF association;2023-02-17
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5. Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation;Molecular Cell;2022-09
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