DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells

Author:

Haynes Teka-Ann S.,Filippov Valery,Filippova Maria,Yang Jun,Zhang Kangling,Duerksen-Hughes Penelope J.

Funder

National Institutes of Health (N.I.H.)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference69 articles.

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3. 1-beta-d-arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells;Strum;J. Biol. Chem.,1994

4. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals;Bose;Cell Death Differ.,1995

5. Daunorubicin-induced apoptosis: triggering ceramide generation through sphingomyelin hydrolysis;Jaffrezou;EMBO J.,1996

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