Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Author:

Lee Phil H.,Anttila Verneri,Won Hyejung,Feng Yen-Chen A.,Rosenthal Jacob,Zhu Zhaozhong,Tucker-Drob Elliot M.,Nivard Michel G.,Grotzinger Andrew D.,Posthuma Danielle,Wang Meg M.-J.,Yu Dongmei,Stahl Eli A.,Walters Raymond K.,Anney Richard J.L.,Duncan Laramie E.,Ge Tian,Adolfsson Rolf,Banaschewski Tobias,Belangero Sintia,Cook Edwin H.,Coppola Giovanni,Derks Eske M.,Hoekstra Pieter J.,Kaprio Jaakko,Keski-Rahkonen Anna,Kirov George,Kranzler Henry R.,Luykx Jurjen J.,Rohde Luis A.,Zai Clement C.,Agerbo Esben,Arranz M.J.,Asherson Philip,Bækvad-Hansen Marie,Baldursson Gísli,Bellgrove Mark,Belliveau Richard A.,Buitelaar Jan,Burton Christie L.,Bybjerg-Grauholm Jonas,Casas Miquel,Cerrato Felecia,Chambert Kimberly,Churchhouse Claire,Cormand Bru,Crosbie Jennifer,Dalsgaard Søren,Demontis Ditte,Doyle Alysa E.,Dumont Ashley,Elia Josephine,Grove Jakob,Gudmundsson Olafur O.,Haavik Jan,Hakonarson Hakon,Hansen Christine S.,Hartman Catharina A.,Hawi Ziarih,Hervás Amaia,Hougaard David M.,Howrigan Daniel P.,Huang Hailiang,Kuntsi Jonna,Langley Kate,Lesch Klaus-Peter,Leung Patrick W.L.,Loo Sandra K.,Martin Joanna,Martin Alicia R.,McGough James J.,Medland Sarah E.,Moran Jennifer L.,Mors Ole,Mortensen Preben B.,Oades Robert D.,Palmer Duncan S.,Pedersen Carsten B.,Pedersen Marianne G.,Peters Triinu,Poterba Timothy,Poulsen Jesper B.,Ramos-Quiroga Josep Antoni,Reif Andreas,Ribasés Marta,Rothenberger Aribert,Rovira Paula,Sánchez-Mora Cristina,Satterstrom F. Kyle,Schachar Russell,Artigas Maria Soler,Steinberg Stacy,Stefansson Hreinn,Turley Patrick,Walters G. Bragi,Werge Thomas,Zayats Tetyana,Arking Dan E.,Bettella Francesco,Buxbaum Joseph D.,Christensen Jane H.,Collins Ryan L.,Coon Hilary,De Rubeis Silvia,Delorme Richard,Grice Dorothy E.,Hansen Thomas F.,Holmans Peter A.,Hope Sigrun,Hultman Christina M.,Klei Lambertus,Ladd-Acosta Christine,Magnusson Pall,Nærland Terje,Nyegaard Mette,Pinto Dalila,Qvist Per,Rehnström Karola,Reichenberg Abraham,Reichert Jennifer,Roeder Kathryn,Rouleau Guy A.,Saemundsen Evald,Sanders Stephan J.,Sandin Sven,St Pourcain Beate,Stefansson Kari,Sutcliffe James S.,Talkowski Michael E.,Weiss Lauren A.,Willsey A. Jeremy,Agartz Ingrid,Akil Huda,Albani Diego,Alda Martin,Als Thomas D.,Anjorin Adebayo,Backlund Lena,Bass Nicholas,Bauer Michael,Baune Bernhard T.,Bellivier Frank,Bergen Sarah E.,Berrettini Wade H.,Biernacka Joanna M.,Blackwood Douglas H.R.,Bøen Erlend,Budde Monika,Bunney William,Burmeister Margit,Byerley William,Byrne Enda M.,Cichon Sven,Clarke Toni-Kim,Coleman Jonathan R.I.,Craddock Nicholas,Curtis David,Czerski Piotr M.,Dale Anders M.,Dalkner Nina,Dannlowski Udo,Degenhardt Franziska,Di Florio Arianna,Elvsåshagen Torbjørn,Etain Bruno,Fischer Sascha B.,Forstner Andreas J.,Forty Liz,Frank Josef,Frye Mark,Fullerton Janice M.,Gade Katrin,Gaspar Héléna A.,Gershon Elliot S.,Gill Michael,Goes Fernando S.,Gordon Scott D.,Gordon-Smith Katherine,Green Melissa J.,Greenwood Tiffany A.,Grigoroiu-Serbanescu Maria,Guzman-Parra José,Hauser Joanna,Hautzinger Martin,Heilbronner Urs,Herms Stefan,Hoffmann Per,Holland Dominic,Jamain Stéphane,Jones Ian,Jones Lisa A.,Kandaswamy Radhika,Kelsoe John R.,Kennedy James L.,Joachim Oedegaard Ketil,Kittel-Schneider Sarah,Kogevinas Manolis,Koller Anna C.,Lavebratt Catharina,Lewis Cathryn M.,Li Qingqin S.,Lissowska Jolanta,Loohuis Loes M.O.,Lucae Susanne,Maaser Anna,Malt Ulrik F.,Martin Nicholas G.,Martinsson Lina,McElroy Susan L.,McMahon Francis J.,McQuillin Andrew,Melle Ingrid,Metspalu Andres,Millischer Vincent,Mitchell Philip B.,Montgomery Grant W.,Morken Gunnar,Morris Derek W.,Müller-Myhsok Bertram,Mullins Niamh,Myers Richard M.,Nievergelt Caroline M.,Nordentoft Merete,Adolfsson Annelie Nordin,Nöthen Markus M.,Ophoff Roel A.,Owen Michael J.,Paciga Sara A.,Pato Carlos N.,Pato Michele T.,Perlis Roy H.,Perry Amy,Potash James B.,Reinbold Céline S.,Rietschel Marcella,Rivera Margarita,Roberson Mary,Schalling Martin,Schofield Peter R.,Schulze Thomas G.,Scott Laura J.,Serretti Alessandro,Sigurdsson Engilbert,Smeland Olav B.,Stordal Eystein,Streit Fabian,Strohmaier Jana,Thorgeirsson Thorgeir E.,Treutlein Jens,Turecki Gustavo,Vaaler Arne E.,Vieta Eduard,Vincent John B.,Wang Yunpeng,Witt Stephanie H.,Zandi Peter,Adan Roger A.H.,Alfredsson Lars,Ando Tetsuya,Aschauer Harald,Baker Jessica H.,Bencko Vladimir,Bergen Andrew W.,Birgegård Andreas,Perica Vesna Boraska,Brandt Harry,Burghardt Roland,Carlberg Laura,Cassina Matteo,Clementi Maurizio,Courtet Philippe,Crawford Steven,Crow Scott,Crowley James J.,Danner Unna N.,Davis Oliver S.P.,Degortes Daniela,DeSocio Janiece E.,Dick Danielle M.,Dina Christian,Docampo Elisa,Egberts Karin,Ehrlich Stefan,Espeseth Thomas,Fernández-Aranda Fernando,Fichter Manfred M.,Foretova Lenka,Forzan Monica,Gambaro Giovanni,Giegling Ina,Gonidakis Fragiskos,Gorwood Philip,Mayora Monica Gratacos,Guo Yiran,Halmi Katherine A.,Hatzikotoulas Konstantinos,Hebebrand Johannes,Helder Sietske G.,Herpertz-Dahlmann Beate,Herzog Wolfgang,Hinney Anke,Imgart Hartmut,Jiménez-Murcia Susana,Johnson Craig,Jordan Jennifer,Julià Antonio,Kaminská Deborah,Karhunen Leila,Karwautz Andreas,Kas Martien J.H.,Kaye Walter H.,Kennedy Martin A.,Kim Youl-Ri,Klareskog Lars,Klump Kelly L.,Knudsen Gun Peggy S.,Landén Mikael,Le Hellard Stephanie,Levitan Robert D.,Li Dong,Lichtenstein Paul,Maj Mario,Marsal Sara,McDevitt Sara,Mitchell James,Monteleone Palmiero,Monteleone Alessio Maria,Munn-Chernoff Melissa A.,Nacmias Benedetta,Navratilova Marie,O’Toole Julie K.,Padyukov Leonid,Pantel Jacques,Papezova Hana,Rabionet Raquel,Raevuori Anu,Ramoz Nicolas,Reichborn-Kjennerud Ted,Ricca Valdo,Roberts Marion,Rujescu Dan,Rybakowski Filip,Scherag André,Schmidt Ulrike,Seitz Jochen,Slachtova Lenka,Slof-Op‘t Landt Margarita C.T.,Slopien Agnieszka,Sorbi Sandro,Southam Lorraine,Strober Michael,Tortorella Alfonso,Tozzi Federica,Treasure Janet,Tziouvas Konstantinos,van Elburg Annemarie A.,Wade Tracey D.,Wagner Gudrun,Walton Esther,Watson Hunna J.,Wichmann H-Erich,Woodside D. Blake,Zeggini Eleftheria,Zerwas Stephanie,Zipfel Stephan,Adams Mark J.,Andlauer Till F.M.,Berger Klaus,Binder Elisabeth B.,Boomsma Dorret I.,Castelao Enrique,Colodro-Conde Lucía,Direk Nese,Docherty Anna R.,Domenici Enrico,Domschke Katharina,Dunn Erin C.,Foo Jerome C.,de. Geus E.J.C.,Grabe Hans J.,Hamilton Steven P.,Horn Carsten,Hottenga Jouke-Jan,Howard David,Ising Marcus,Kloiber Stefan,Levinson Douglas F.,Lewis Glyn,Magnusson Patrik K.E.,Mbarek Hamdi,Middeldorp Christel M.,Mostafavi Sara,Nyholt Dale R.,Penninx Brenda WJH.,Peterson Roseann E.,Pistis Giorgio,Porteous David J.,Preisig Martin,Quiroz Jorge A.,Schaefer Catherine,Schulte Eva C.,Shi Jianxin,Smith Daniel J.,Thomson Pippa A.,Tiemeier Henning,Uher Rudolf,van der Auwera Sandra,Weissman Myrna M.,Alexander Madeline,Begemann Martin,Bramon Elvira,Buccola Nancy G.,Cairns Murray J.,Campion Dominique,Carr Vaughan J.,Cloninger C. Robert,Cohen David,Collier David A.,Corvin Aiden,DeLisi Lynn E.,Donohoe Gary,Dudbridge Frank,Duan Jubao,Freedman Robert,Gejman Pablo V.,Golimbet Vera,Godard Stephanie,Ehrenreich Hannelore,Hartmann Annette M.,Henskens Frans A.,Ikeda Masashi,Iwata Nakao,Jablensky Assen V.,Joa Inge,Jönsson Erik G.,Kelly Brian J.,Knight Jo,Konte Bettina,Laurent-Levinson Claudine,Lee Jimmy,Lencz Todd,Lerer Bernard,Loughland Carmel M.,Malhotra Anil K.,Mallet Jacques,McDonald Colm,Mitjans Marina,Mowry Bryan J.,Murphy Kieran C.,Murray Robin M.,O’Neill F. Anthony,Oh Sang-Yun,Palotie Aarno,Pantelis Christos,Pulver Ann E.,Petryshen Tracey L.,Quested Digby J.,Riley Brien,Sanders Alan R.,Schall Ulrich,Schwab Sibylle G.,Scott Rodney J.,Sham Pak C.,Silverman Jeremy M.,Sim Kang,Steixner Agnes A.,Tooney Paul A.,van Os Jim,Vawter Marquis P.,Walsh Dermot,Weiser Mark,Wildenauer Dieter B.,Williams Nigel M.,Wormley Brandon K.,Zhang Fuquan,Androutsos Christos,Arnold Paul D.,Barr Cathy L.,Barta Csaba,Bey Katharina,Bienvenu O. Joseph,Black Donald W.,Brown Lawrence W.,Budman Cathy,Cath Danielle,Cheon Keun-Ah,Ciullo Valentina,Coffey Barbara J.,Cusi Daniele,Davis Lea K.,Denys Damiaan,Depienne Christel,Dietrich Andrea,Eapen Valsamma,Falkai Peter,Fernandez Thomas V.,Garcia-Delgar Blanca,Geller Daniel A.,Gilbert Donald L.,Grados Marco A.,Greenberg Erica,Grünblatt Edna,Hagstrøm Julie,Hanna Gregory L.,Hartmann Andreas,Hedderly Tammy,Heiman Gary A.,Heyman Isobel,Hong Hyun Ju,Huang Alden,Huyser Chaim,Ibanez-Gomez Laura,Khramtsova Ekaterina A.,Kim Young Key,Kim Young-Shin,King Robert A.,Koh Yun-Joo,Konstantinidis Anastasios,Kook Sodahm,Kuperman Samuel,Leventhal Bennett L.,Lochner Christine,Ludolph Andrea G.,Madruga-Garrido Marcos,Malaty Irene,Maras Athanasios,McCracken James T.,Meijer Inge A.,Mir Pablo,Morer Astrid,Müller-Vahl Kirsten R.,Münchau Alexander,Murphy Tara L.,Naarden Allan,Nagy Peter,Nestadt Gerald,Nestadt Paul S.,Nicolini Humberto,Nurmi Erika L.,Okun Michael S.,Paschou Peristera,Piras Fabrizio,Piras Federica,Pittenger Christopher,Plessen Kerstin J.,Richter Margaret A.,Rizzo Renata,Robertson Mary,Roessner Veit,Ruhrmann Stephan,Samuels Jack F.,Sandor Paul,Schlögelhofer Monika,Shin Eun-Young,Singer Harvey,Song Dong-Ho,Song Jungeun,Spalletta Gianfranco,Stein Dan J.,Stewart S Evelyn,Storch Eric A.,Stranger Barbara,Stuhrmann Manfred,Tarnok Zsanett,Tischfield Jay A.,Tübing Jennifer,Visscher Frank,Vulink Nienke,Wagner Michael,Walitza Susanne,Wanderer Sina,Woods Martin,Worbe Yulia,Zai Gwyneth,Zinner Samuel H.,Sullivan Patrick F.,Franke Barbara,Daly Mark J.,Bulik Cynthia M.,Lewis Cathryn M.,McIntosh Andrew M.,O’Donovan Michael C.,Zheutlin Amanda,Andreassen Ole A.,Børglum Anders D.,Breen Gerome,Edenberg Howard J.,Fanous Ayman H.,Faraone Stephen V.,Gelernter Joel,Mathews Carol A.,Mattheisen Manuel,Mitchell Karen S.,Neale Michael C.,Nurnberger John I.,Ripke Stephan,Santangelo Susan L.,Scharf Jeremiah M.,Stein Murray B.,Thornton Laura M.,Walters James T.R.,Wray Naomi R.,Geschwind Daniel H.,Neale Benjamin M.,Kendler Kenneth S.,Smoller Jordan W.

Funder

Research Council of Norway

South East Norway Health Authority

Klarman Family Foundation

Swedish Research Council

National Institute of Mental Health

NIAAA

Lundbeck Foundation

Stanley Foundation

the Simons Foundation

NIMH

Novo Nordisk Foundation

NIH

Tourette Association of America

David Judah Foundation

National Center for Biotechnology Information

Collaborative Study on the Genetics of Alcoholism

Collaborative Genetic Study of Nicotine Dependence

Family Study of Cocaine Dependence

National Institute on Alcohol Abuse and Alcoholism

NIDA

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

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