Aberrant tolerogenic functions and proinflammatory skew of dendritic cells in STAT1 gain-of-function patients may contribute to autoimmunity and fungal susceptibility

Author:

Parackova Zuzana,Zentsova Irena,Vrabcova Petra,Sediva Anna,Bloomfield Marketa

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference51 articles.

1. Human inborn errors of immunity: 2019 update of the IUIS phenotypical classification;Bousfiha;J. Clin. Immunol.,2020

2. Clinical relevance of gain- and loss-of-function germline mutations in STAT1: a systematic review;Zhang;Front. Immunol.,2021

3. Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype;Toubiana;Blood,2016

4. Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC);Zheng;Eur. J. Immunol.,2015

5. Autoimmune regulator deficiency results in a decrease in STAT1 levels in human monocytes;Zimmerman;Front. Immunol.,2017

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