Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro

Author:

Xie Sai-li,Zhu Xiayan,Gao Nanyong,Lin Qianmeng,Chen Chaojie,Yang Yun-jun,Cai Jian-ping,Hu Guo-xin,Xu Ren-ai

Funder

Wu Jieping Medical Foundation

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference48 articles.

1. Pharmacogenomics of triazole antifungal agents: implications for safety, tolerability and efficacy;Amsden;Expet Opin. Drug Metabol. Toxicol.,2017

2. Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos;Dai;J. Pharmacol. Exp. Therapeut.,2001

3. Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro;Fang;Drug Des. Dev. Ther.,2017

4. The Pharmacogene variation (PharmVar) Consortium: incorporation of the human cytochrome P450 (CYP) allele nomenclature database;Gaedigk;Clin. Pharmacol. Ther.,2018

5. Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation;Gomez-Lopez;Clin. Microbiol. Infect.,2020

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