Neuroprotective effect of diosmin against chlorpyrifos-induced brain intoxication was mediated by regulating PPAR-γ and NF-κB/AP-1 signals

Author:

Abd-Elhamid Tarek HamdyORCID,Althumairy Duaa,Bani ismail MohammadORCID,Abu Zahra HamadORCID,Seleem Hanan S.,Hassanein Emad H.M.,Ali Fares E.M.ORCID,Mahmoud Amany Refaat

Publisher

Elsevier BV

Reference76 articles.

1. Diosmin attenuates methotrexate-induced hepatic, renal, and cardiac injury: a biochemical and histopathological study in mice;Abdel-Daim;Oxid. Med. Cell. Longev.,2017

2. Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats;Abolaji;Chem. Biol. Interact.,2017

3. Chlorpyrifos (from different sources): effect on testicular biochemistry of male albino rats;Afaf,2010

4. Diosmin modulates the NF-kB signal transduction pathways and downregulation of various oxidative stress markers in alloxan-induced diabetic nephropathy;Ahmed,2016

5. Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK pathway;AlAsmari;A Preclinical Study,2021

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