Fraxin represses NF-κB pathway via inhibiting the activation of epidermal growth factor receptor to ameliorate diabetic renal tubulointerstitial fibrosis

Author:

Zeng Jingran,Liang Liyin,Chen Rui,Li Chuting,Pan Linjie,Wen Min,Lv Dongxin,Liu Min,Xu Zhanchi,Huang Heqing

Funder

National Natural Science Foundation of China

Special Project for Research and Development in Key areas of Guangdong Province

Publisher

Elsevier BV

Subject

Pharmacology

Reference54 articles.

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3. EGFR signaling promotes TGFbeta-dependent renal fibrosis;Chen;J. Am. Soc. Nephrol.,2012

4. Fraxin promotes the activation of Nrf2/ARE pathway via increasing the expression of Connexin43 to ameliorate diabetic renal fibrosis;Chen;Front. Pharmacol.,2022

5. The epithelial-to-mesenchymal transition as a possible therapeutic target in fibrotic disorders;Di Gregorio;Front. Cell Dev. Biol.,2020

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