Commentary: Critical questions, misconceptions and a road map for improving the use of the lymphocyte cytokinesis-block micronucleus assay for in vivo biomonitoring of human exposure to genotoxic chemicals—A HUMN project perspective

Author:

Kirsch-Volders Micheline,Bonassi StefanoORCID,Knasmueller Siegfried,Holland Nina,Bolognesi Claudia,Fenech Michael F.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference86 articles.

1. Reflections on the development of micronucleus assays;Heddle;Mutagenesis,2011

2. Test No. 487: In Vitro Mammalian Cell Micronucleus Test. OECD Guidelines for the Testing of Chemicals, Section 4. Health Effects;OECD Library,2010

3. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells;Fenech;Mutagenesis,2011

4. Cytogenetic Dosimetry: Applications in Preparedness for and Response to Radiation Emergencies;IAEA,2011

5. Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies;Bonassi;Mutagenesis,2011

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