Assessment of the Artemia salina toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom

Author:

Araya Xavier,Okumu Mitchel,Durán Gina,Gómez Aarón,Gutiérrez José María,León GuillermoORCID

Funder

Wellcome Trust

Universidad de Costa Rica

Publisher

Elsevier BV

Reference38 articles.

1. CIOMS (Council of International Organizations of medical sciences);Bankowski;International guiding principles for biomedical research involving animals. Geneva,1985

2. Comparative studies of the venom of a new Taipan species, Oxyuranus temporalis, with other members of its genus;Barber;Toxins,2014

3. Determination of the neutralizing potency of horse antivenom against bothropic and crotalic venoms by indirect enzyme immunoassay;Barbosa;Braz. J. Med. Biol. Res.,1995

4. An Introduction to the Study of Experimental Medicine;Bernard,1957

5. The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay;Chacón;Toxicon,2015

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