Eculizumab in Asian patients with anti-aquaporin-IgG-positive neuromyelitis optica spectrum disorder: A subgroup analysis from the randomized phase 3 PREVENT trial and its open-label extension

Author:

Kim Ho JinORCID,Nakashima Ichiro,Viswanathan Shanthi,Wang Kai-Chen,Shang Shulian,Miller Larisa,Yountz Marcus,Wingerchuk Dean M.ORCID,Pittock Sean J.,Levy Michael,Berthele AchimORCID,Totolyan Natalia,Palace Jacqueline,Barnett Michael H.,Fujihara Kazuo

Funder

Alexion Pharmaceuticals Inc

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology,General Medicine

Reference41 articles.

1. Pharmacokinetic/pharmacodynamic properties of eculizumab support established efficacy in patients with NMOSD: findings from the phase 3 PREVENT study;Berthele;Eur. J. Neurol.,2020

2. Meningococcal disease in the Asia-Pacific region: findings and recommendations from the Global Meningococcal Initiative;Borrow;Vaccine,2016

3. Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria;Brodsky;Blood,2008

4. Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial;Cree;Lancet,2019

5. EuroQol Research Foundation, 2018. EQ-5D-3L user guides. 2018. https://euroqol.org/publications/user-guides. Accessed December 7, 2020.

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