S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple intracellular signalling in Th1, Th17, and treg cells-Reference-Cited by-同舟云学术

S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple intracellular signalling in Th1, Th17, and treg cells

Published:2023-05 Issue: Volume:73 Page:104658
ISSN:2211-0348
Container-title:Multiple Sclerosis and Related Disorders
language:en
Short-container-title:Multiple Sclerosis and Related Disorders

Author:

Ahmad Sheikh F.^ORCID,Ansari Mushtaq A.,Nadeem Ahmed,Bakheet Saleh A.,Al-Mazroua Haneen A.,Alomar Hatun A.,Al-Hamamah Mohammed A.,Attia Sabry M.

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology,General Medicine

Reference72 articles.

1. S3I-201, a selective Stat3 inhibitor, restores neuroimmune function through upregulation of Treg signaling in autistic BTBR T+ Itpr3tf/J mice;Ahmad;Cell Signal,2018

2. The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T+ Itpr3tf/J mouse model of autism;Ahmad;Brain Res. Bull.,2019

3. CC chemokine receptor 5 antagonist alleviates inflammation by regulating IFN-γ/IL-10 and STAT4/Smad3 signaling in a mouse model of autoimmune encephalomyelitis;Ahmad;Cell Immunol.,2022

4. Pharmacological inhibition of STAT3 by stattic ameliorates clinical symptoms and reduces autoinflammation in myeloid, lymphoid, and neuronal tissue compartments in relapsing-remitting model of experimental autoimmune encephalomyelitis in SJL/J Mice;Alhazzani;Pharmaceutics,2021

5. Adenosine A2A receptor modulates neuroimmune function through Th17/retinoid-related orphan receptor gamma t (RORγt) signaling in a BTBR T+ Itpr3tf/J mouse model of autism;Ansari;Cell Signal,2017

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