The Folding and Dimerization of HIV-1 Protease: Evidence for a Stable Monomer from Simulations
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference49 articles.
1. Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease;Wlodawer;Science,1989
2. X-ray analysis of HIV-1 protease at 2.7Å resolution confirms structural homology among retroviral enzymes;Lapatto;Nature,1989
3. Flap opening and dimer-interface flexibility in the free and inhibitor-bound HIV protease, and their implications for function;Ishima;Structure,1999
4. Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance;Scott;Structure,2000
5. Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations;Freedberg;Protein Sci.,2002
Cited by 86 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Evolution of drug resistance drives destabilization of flap region dynamics in HIV-1 protease;Biophysical Reports;2023-09
2. Mechanism of darunavir binding to monomeric HIV-1 protease: a step forward in the rational design of dimerization inhibitors;Physical Chemistry Chemical Physics;2022
3. The denatured state of HIV ‐1 protease under native conditions;Proteins: Structure, Function, and Bioinformatics;2021-08-03
4. Experiments and simulation on ZIKV NS2B-NS3 protease reveal its complex folding;Virology;2021-04
5. A Molecular Dynamics Study of the Inhibition of Monomeric HIV‐1 Protease as An Alternative to Overcome Drug Resistance by RNA Aptamers as A Therapeutic Tool;ChemistrySelect;2020-08-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3