Photosensitivity and cGAS-Dependent IFN-1 Activation in Patients with Lupus and TREX1 Deficiency
Author:
Funder
Roche
Deutsche Forschungsgemeinschaft
Technische Universität Dresden
Publisher
Elsevier BV
Subject
Cell Biology,Dermatology,Molecular Biology,Biochemistry
Reference39 articles.
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2. TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner;Ablasser;J Immunol,2014
3. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus;Crow;Nat Genet,2006
4. Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing;Gehrke;Immunity,2013
5. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs;Gibson;Nat Rev Mol Cell Biol,2012
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