PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes

Author:

Zhao JiahuiORCID,Munanairi AdmireORCID,Liu Xian-YuORCID,Zhang JieORCID,Hu LinghanORCID,Hu MeiqinORCID,Bu DingfangORCID,Liu LinglingORCID,Xie ZhiqiangORCID,Kim Brian S.ORCID,Yang YongORCID,Chen Zhou-FengORCID

Funder

National Natural Science Foundation of China

China National Funds for Distinguished Young Scientists

CAMS Innovation Fund for Medical Sciences

NIH

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference58 articles.

1. Involvement of TRPV4 in serotonin-evoked scratching;Akiyama;J Invest Dermatol,2016

2. Association of a mutation in TRPV3 with defective hair growth in rodents;Asakawa;J Invest Dermatol,2006

3. PAR2 Pepducin-based suppression of inflammation and itch in atopic dermatitis models;Barr;J Invest Dermatol,2019

4. Why we scratch an itch: the molecules, cells and circuits of itch;Bautista;Nat Neurosci,2014

5. Th2 cytokines and atopic dermatitis;Brandt;J Clin Cell Immunol,2011

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