Keratinocyte-Specific SOX2 Overexpression Suppressed Pressure Ulcer Formation after Cutaneous Ischemia–Reperfusion Injury via Enhancement of Amphiregulin Production

Author:

Inoue YutaORCID,Uchiyama AkihikoORCID,Amalia Syahla NisaaORCID,Ishikawa MaiORCID,Kosaka KeijiORCID,Sekiguchi AkikoORCID,Ogino SachikoORCID,Yokoyama YokoORCID,Torii RyokoORCID,Hosoi MariORCID,Akai RyokoORCID,Iwawaki TakaoORCID,Morasso Maria I.ORCID,Motegi Sei-ichiroORCID

Funder

Japanese Dermatological Association

Japan Society for the Promotion of Science

Kose Cosmetology Research Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference46 articles.

1. Surviving in skin pathologies;Bongiovanni;Exp Dermatol,2011

2. A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin;Cook;Mol Cell Biol,1991

3. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement;Emmerson;EMBO Mol Med,2018

4. A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies;Härkönen;Redox Biol,2023

5. Transcriptional signature primes human oral mucosa for rapid wound healing;Iglesias-Bartolome;Sci Transl Med,2018

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